Monday, July 1, 2019

For Suboxone Memphis Is Worth Visiting

By Douglas Fox


The US has been struggling with the epidemic of opiate use for quite some time now. Statistics show that millions of Americans are addicted to opiate substances of some sort. The level of dependence on these substances is overwhelming. As such, solutions are being invented to help people who are already addicted to opiates so that they can stop depending on them. When one needs Suboxone Memphis offers the perfect location to visit.

One of the most common solutions that was developed to help people with opiate addiction stop their addiction is suboxone. The term suboxone itself has been a blockbuster for as long as the drug has existed. This drug was developed because it has the potential of reducing symptoms of opiate withdrawal and addiction. As such, it is meant to be taken by addicts to help them stop using illicit drugs.

Billions of dollars are made in revenue by manufacturers of these drugs. They made more than 1.55 billion in the year 2013 alone. The drug made more sales than Viagra and Adderall. Suboxone is seen as a better and safer option in comparison to methadone in the face of such an overwhelming opioid abuse epidemic.

This drug is composed of two different individual drugs, that is, buprenorphine and naloxone. Naloxone is a pure opioid antagonist while buprenorphine is a partial opioid agonist. Given the nature of these two drugs, they serve different purposes in helping with addiction. The work of buprenorphine is to deliver the blood stream with diminished doses of opioid because it is an opioid agonist.

The dimished doses are much lower to the larger doses that the addict is used too. In the end, the effect of these diminished doses is that the person gets weaned off their addiction, with minimum opioid withdrawal symptoms. Being a partial agonist, buprenorphine activates opioid receptors in the brain only partially unlike opioid drugs themselves that are classified as full agonists. Thus, the effects of drug use that one experiences after using buprenorphine are quite low.

Opioid receptors in the brain get activated by agonists. On the contrary, the receptors are shut down by antagonists. Shutting down agonists and opioid receptors prevents the effects of agonists from reaching the nervous system. This is because the effects are reversed and blocked. Antagonists also blocks effects that were already in the system. This helps in stopping addiction. This is how naloxone works given that it is an antagonist.

Blocking and reversing the effects of opioids in the body causes withdrawal symptoms in a patient. There is a wide range of withdrawal symptoms that include but are not limited to insomnia, nausea, wild mood swings, diarrhea, irritability, agitation, vomiting, and muscle cramping. How much one was addicted before taking the drug will determine how severe the symptoms they have are. Those that were heavily addicted experience very severe symptoms that include fatal seizures and respiratory failure.

It is the risks that naloxone carries when administered alone that makes it necessary to have it combined with buprenorphine. Buprenorphine acts to give the patient an easier time during the weaning process. Even though this drug is meant to do good, people often abuse it too by using too much of it that they develop an addiction. This has become a problem in itself.




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